Cat. No.
MABL-3895
Application
radiolabelling, therapeutic, IHC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
A5B7
From
Recombinant Antibody
Specificity
This antibody is specific for human CEA.
Alternative Names
CEA; CD66; Q7KZ28; Q13985; Q14081
UniProt
Q13982
Immunogen
The original antibody was generated by immunizing KAC mice (KAC mouse is a genetically engineered mouse strain that expresses BAP -Biotin Accepting Peptide, sequence on constant part of kappa chain) subcutaneously with CD155-Fc fusion protein.
Application Notes
This antibody was used to identify CD155 expression on U-87 MG and U-87 MG PVRhi cell lines using flow cytometry. This antibody was used in the generation of anti-CD155 -saporin and anti- CD155-diphtheria immunotoxins and were tested for its antitumor activity. Cytotoxic effect was determined by ToxiLight kit. The results suggested that the immunotoxins were successful in killing CD155 expressing tumor cells.(WO2019102456).
Antibody First Published
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
