Cat. No.
MABL-3501
Application
ELISA
Isotype
Engineer antibody
Species Reactivity
InfluenzaAVirus (severalsubtypes)
Clone No.
HA
From
Recombinant Antibody
Specificity
This antibody specifically recognizes the conformational epitope in the stem region of HA in which amino acid sequences are highly conserved in H1N1, H5N1, H6N1, and H9N2 subtypes of Influenza A viru This antibody uses the VH1-69*01, D3-10*01, JH5*02, VL2D-29*02 and JL4. This antibody does not cross react with HA in H2N2, H3N2 and H7N7 subtype of Influenza A Virus. This antibody has no effect on haemagglutination-inhibition activity.
Alternative Names
hemagglutinin; haemagglutinin
UniProt
Immunogen
Made by immortalizing IgG-expressing B cells from individuals following vaccination with seasonal influenza vaccine, containing H1 and H3 influenza Virus subtypes.
Application Notes
Antibody First Published
Corti, D. et al. Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine. J Clin Invest 120, 1663–1673 (2010).PMID:20389023
Note on publication
Describes the isolation and analysis of a panel of human antibodies from vaccinated individuals and its evaluation using Virus neutralization assays.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
