Cat. No.
MABL-3531
Application
NTRL, ELISA
Isotype
Engineer antibody
Species Reactivity
SARSCoronavirus
Clone No.
S228
From
Recombinant Antibody
Specificity
SARS-CoV-neutralizing hmAbs, binds to SARS-CoV S glycoprotein, inhibiting the binding of the glycoprotein to human ACE2.
Alternative Names
Severe Acute Respiratory Syndrome Coronavirus GP
UniProt
Immunogen
Made by immortalizing IgG-expressing B cells from recovered SARS patients.
Application Notes
Antibody First Published
Rockx B, Corti D, Donaldson E, Sheahan T, Stadler K, Lanzavecchia A, Baric R. Structural basis for potent cross-neutralizing human monoclonal antibody protection against lethal human and zoonotic Severe Acute Respiratory Syndrome CoronaVirus challenge. J Virol. 2008 Apr;82(7):3220-35. doi: 10.1128/JVI.02377-07. Epub 2008 Jan 16. PMID:18199635
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
