Cat. No.
MABL-3545
Application
Biacore, NTRL, ELISA
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
GCA43
From
Recombinant Antibody
Specificity
This antibody binds to human GM-CSF at a site distinct to clone GCC21.
Alternative Names
GMCSF; granulocyte–macrophage colony-stimulating factor; CSF2
UniProt
P04141
Immunogen
Antibody generated by sequencing of memory B-cells obtained from human patients suffering from chronic autoimmune pulmonary alveolar proteinosis.
Application Notes
This antibody binds to human GM-CSF and has neutralizing activity.
Antibody First Published
Piccoli et al. Neutralization and clearance of GM-CSF by autoantibodies in pulmonary alveolar proteinosis Nat Commun. 2015 Jun 16;6:7375 PMID:26077231
Note on publication
Describes the generation and characterization of this antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
