Key features and details | |
Cat. No. | MABL-2945 |
Name | Anti-SOD1 mAbs |
Clone No. | AFD- 591-37-M1 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | in vivo, IP, ELISA, FC, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody is specific for misfolded SOD1. |
Alternative Name | SOD1; SOD1G93A; SOD1 A4V |
UniProt | |
Immunogen | The original antibody was raised by immunizing mice with Trx-bhSOD1-A4V. |
Application Notes | This antibody was used for an ELISA on b-hSOD1, b-hSOD1-A4V, b-hSOD1-G85R and b- hSOD1-G93A. This antibody was used for immunoprecipitation on HEK-293T cells transfected with mutated human SOD1. The antibody was used for immunofluorescence on HEK-293T cells transiently transfected with hSOD1-G93A. The antibody was also used for immunohistochemistry on tissue from a mouse model of ALS, and on spinal cords of sporadic ALS patients, the mice expressed either hSOD1 or hSOD1-G93A. This antibody was used in vivo on mouse ALS models. It showed that the mice treated with the antibody maintained better weight and extended life (US9663586B2). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
