Cat. No.
MABL-3882
Application
IP, WB, IHC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
bcl-2/124
From
Recombinant Antibody
Specificity
This antibody recognises human BLC-2 which is an antiapoptotic factor in various cell types. Its disregulation was implicated in different conditions, such as cancers and autoimmune disorders.
Alternative Names
Apoptosis regulator Bcl-2; AW986256; B-cell CLL/lymphoma 2; Bcl-2; C430015F12Rik; D630044D05Rik; D830018M01Rik; protein phosphatase 1; regulatory subunit 50; bcl-2- 124; bcl2/124
UniProt
P10415
Immunogen
Human recombinant Breast Epithelial Mucin.
Application Notes
The antibody binds to human breast epithelial mucin, a gel forming extracellular protein frequently overexpressed in human cancers.
Antibody First Published
Couto et al. Cloning of cDNAs encoding the variable domains of antibody BrE-3 and construction of a chimeric antibody. Hybridoma 1993; 12(1):15--23 PMID:8454302
Note on publication
Describes the generation of a chimeric human/mouse anti-mucin antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
