Cat. No.
MABL-200
Application
ICC, WB
Isotype
Engineer antibody
Species Reactivity
Mouse
Clone No.
N98/7R
From
Recombinant Antibody
Specificity
This antibody is specific for neuroligin-4*. Neuroligin-4* is a cell surface protein involved in cell- cell-interactions. Plays a role in the formation or maintenance of synaptic junctions via its interactions (via the extracellular domains) with neurexin family members. Plays a role in synaptic signal transmission.
Alternative Names
Neuroligin 4-like; Nlgn4l; Neuroligin-4; NL-4; N98/7
UniProt
B0F2B4
Immunogen
This antibody was raised against a fusion protein of amino acids 782-945 of mouse Neuroligin-4*.
Application Notes
This antibody is recommended for detection and analysis of neuroligin-4 by immunocytochemistry and western blot. For instance, the mouse version of this antibody was used to detect neuroligin-4 by western blot in extracts of MBM and COS cells transiently transfected with Neuroligin- 1 and Neuroligin-4 plasmids.
Antibody First Published
Andrews et al. A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced multiplex immunolabeling of brain eLife. 2019; 8: e43322. PMID:30667360
Note on publication
Describes the generation of a library of recombinant monoclonal antibodies (R- mAbs) from a pool of mAb-producing hybridomas for neuroscience research.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.