Cat. No.
MABL-231
Application
FC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
R22
From
Recombinant Antibody
Specificity
This antibody is specific for human CD39. CD39 could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well.
Alternative Names
Ectonucleoside triphosphate diphosphohydrolase 1; ENTPD1; NTPDase 1; Ecto-ATP diphosphohydrolase 1; Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Lymphoid cell activation antigen
UniProt
P49961
Immunogen
The mouse version of this antibody was raised by immunizing a BALB/c rat with JY cells.
Application Notes
To study the expression and distribution of CD39, flow cytometry was performed on PBMCs and splenic e-cells using the mouse version of this antibody (Kansas et al, 1991; pmid:1672348).
Antibody First Published
Kansas et al. Expression, distribution, and biochemistry of human CD39. Role in activation-associated homotypic adhesion of lymphocytes J Immunol. 1991 Apr 1;146(7):2235-44. PMID:1672348
Note on publication
The distribution, biochemical properties, and function of CD39 were characterized with the use of antibodies.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
