Key features and details | |
Cat. No. | MABL-464 |
Name | Anti-Autotaxin mAbs |
Clone No. | AFD- ATXB3 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | SPR, ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody is specific for autotaxin, a secreted lysophospholipase D. In mammals, the enzyme produces phospholipid lysophosphatidic acid (LPA) from lysophosphatidylcholine (LPC). |
Alternative Name | ATX; Extracellular lysophospholipase D; LysoPLD; ectonucleotide pyrophosphatases/phosphodiesterases 2; ectonucleotide pyrophosphatase/phosphodiesterase family member 2; E-NPP 2; ENPP2; EC |
UniProt | Q13822 |
Immunogen | The original antibody was generated by panning a de novo human Fab-pIX library against biotinylated human ATX beta. |
Application Notes | The specificity of the original antibody (human Fab) was evaluated via an ELISA, with a binding affinity (KD) of 0.715 nM as measured by SPR. This antibody can be used as part of an antibody pair with Ab04781 [ATXB6] since they exhibit simultaneous binding to ATX (US20150087812A1). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
