Key features and details | |
Cat. No. | MABL-463 |
Name | Anti-ATRX mAbs |
Clone No. | AFD- 20A2 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB, ELISA, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody recognizes ATRX protein. ATRX protein is involved in transcriptional regulation and chromatin remodeling and it facilitates DNA replication in multiple cellular environments and is required for efficient replication of a subset of genomic loci. |
Alternative Name | X Linked Alpha Thalassemia; Transcriptional regulator ATRX; ATP- dependent helicase ATRX; X-linked helicase II; X-linked nuclear protein; XNP; Znf-HX; TS1; CGMCC NO 20772 : |
UniProt | P46100 |
Immunogen | The original antibody was generated by immunizing a mouse with the recombinant ATRX protein. |
Application Notes | The antibody 20A2 and the commercial antibody TS1 were used to stain pancreatic neuroendocrine and cerebral gel tumors in immunohistochemistry. The results of the two antibodies were comparable and the staining intensity of the antibody 20A2 was higher than the commercial antibody (CN112940133A). |
Antibody First Published | |
Note on publication | |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |