Cat. No.
MABL-3470
Application
FC
Isotype
Engineer antibody
Species Reactivity
Mouse
Clone No.
OX131
From
Recombinant Antibody
Specificity
Mouse CD200R, an inhibitory receptor which is expressed on various leukocytes and delivers inhibitory signals upon engagement with its ligand CD200R1 and CD200R2.
Alternative Names
CD200 Receptor; CD200 Cell surface glycoprotein receptor; Cell surface glycoprotein OX2 receptor 1; CD200R1; CD200R; OX2R; CD200 receptor-like 2; HuCD200R2; CD200RLa
UniProt
Q9ES57
Immunogen
Recombinant protein consisting of the extracellular regions of CD200R and CD200RLc together with rCD4d3+4 and attachment to streptavidin coated beads.
Application Notes
Antibody First Published
Akkaya M, Aknin ML, Akkaya B, Barclay AN. Dissection of agonistic and blocking effects of CD200 receptor antibodies. PLoS One. 2013 May 14;8(5):e63325. PMID: 23691022
Note on publication
Describes the generation of the antibody, shows it blocks CD200/CD200R interaction by binding to CD200R (Uniprot Accession No. Q9ES57; Q9ES57.1).
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
