Cat. No.
MABL-207
Application
WB, IF
Isotype
Engineer antibody
Species Reactivity
Rat
Clone No.
N121A/31R
From
Recombinant Antibody
Specificity
This antibody is specific for pannexin-2. It does not cross-react with Pannexin-1 or Pannexin-3. Pannexin-2 is a structural component of the gap junctions and the hemichannels.
Alternative Names
Panx2; N121A/31
UniProt
P60571
Immunogen
This antibody was raised against a fusion protein of amino acids 11-664 of rat Pannexin-2.
Application Notes
Immunofluorescence was preformed on mouse tissue with this antibody (Le Vasseur et al, 2014; PMID:25505382). Immunoblotting was preformed on tissue lysate from spinal cords of mice (Le Vasseur et al, 2014; PMID:25505382).
Antibody First Published
Le Vasseur et al. Pannexin 2 protein expression is not restricted to the CNS Front Cell Neurosci. 2014 Nov 25;8:392. PMID:25505382
Note on publication
A novel commercial monoclonal antibodies was charatarized and Panx2 expression was surveyed and distribution at the mRNA and protein level by real-time qPCR, Western blotting and immunofluorescence was studied.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
