Cat. No.
MABL-208
Application
WB
Isotype
Engineer antibody
Species Reactivity
Rat, Mouse
Clone No.
N111/24R
From
Recombinant Antibody
Specificity
This antibody is specific for mitofusin-1. It shows no cross-reactivity against Mitofusin-2.
Alternative Names
Mfn1; Transmembrane GTPase MFN1; N111/24
UniProt
Q811U4
Immunogen
This antibody was raised against a fusion protein of amino acids 350-580 of mouse Mitofusin- 1.
Application Notes
Immunoblotting was preformed on whole cardiac extracts from mice with this antibody (Papanicolaou et al, 2012; PMID:22037195).
Antibody First Published
Papanicolaou et al. Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death Am J Physiol Heart Circ Physiol. 2012 Jan 1;302(1):H167-79. PMID:22037195
Note on publication
The generation and initial characterization of cardiomyocyte-specific Mfn-1 knockout (Mfn-1 KO) mice was reported.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
