Cat. No.
MABL-3727
Application
IP, WB, Block, ELISA, FC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
Bevacizumab
From
Recombinant Antibody
Specificity
This antibody binds native and reduced human VEGF (isoform 165).
Alternative Names
ascular Endothelial Growth Factor; VEGF-A; VEGFA; Vascular Permeability Factor; VPF
UniProt
P15692
Immunogen
Recombinant human VEGF.
Application Notes
This is a research-grade biosimilar against VEGF. VEGF is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels.
Antibody First Published
Kim et al. The Vascular Endothelial Growth Factor Proteins: Identification of biologically relelvant regions by neutralizing monoclonal antibodies. Growth Factors. 1992;7(1):53-64.PMID:1380254
Note on publication
Describes generation of anti-hVEGF monoclonal antibodies as well as characterisation of binding by various methods. Also shows inhibition of angiogenesis and vascular permeabilization induced by human VEGF in a model organisms.
Size
208 μg Purified antibody.
Concentration
109 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 408.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 128⁰C.
![Anti-VEGF [Bevacizumab] (MABL-](/public/static/common/images/not_adv.jpg)
