Cat. No.
MABL-3846
Application
ELISA
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
8G8F5
From
Recombinant Antibody
Specificity
The antibody binds specificially to human PSA.
Alternative Names
KLK3; Human prostate-specific antigen
UniProt
P07288
Immunogen
Purified Seminal PSA.
Application Notes
This antibody binds to human prostate-specific antigen, which hydrolyzes semenogelin-1 triggering the liquifaction of the seminal coagulum. The antibody enhances enzymatic activity by stabilisng the open and active conformation.
Antibody First Published
Ménez et al. Crystal structure of a ternary complex between human prostate-specific antigen, its substrate acyl intermediate and an activating antibody. Journal of Molecular Biology 2008; 376(4):1021-1033 PMID:18187150
Note on publication
Describes the crystallisation of a new monoclonal antibody in complex with human PSA.
Size
327 μg Purified antibody.
Concentration
228 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 527.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 247⁰C.
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