Cat. No.
MABL-5888
Type
Mouse antibody Monoclonal.
Clone No
Shipped
Shipped with Ice Packs
Description
Shiga like toxin 2B monoclonal antibody IgG & IgG2B derived from mouse, immunized with recombinant Shiga-like toxin 2 subunit B ( E. coli O157:H7). The subunit B has nontoxic action and is a functional region which binds to the receptor. Shiga-like toxin 2 subunit B contains full amino acid sequence and forms pentamer binding to the host cell receptor.
Synonyms
Introduction
Shiga-like toxin (verotoxin) is a toxin produced by some strains of Escherichia coli. Shiga-like toxin is named for its similarity to the AB5-type Shiga toxin produced by the bacteria Shigella dysenteriae. There are two known types-SLT1 and SLT2. The Shiga-like toxin is linked with hemolytic-uremic syndrome. Shiga-like toxin requires highly specific receptors on the cells'' surface in order to attach and enter the cell. Species such as cattle, swine, and deer which do not carry these receptors may harbor toxigenic bacteria without any ill effect, dropping them in their feces, from where they may be distributed to humans. Shiga Like Toxin-1 Subunit B has nontoxic action, it is the functional region which binds to the receptor. The Shiga Like Toxin-1 Subunit B can be useful in vaccine study, antibody test and other functional research.
Physical Appearance
Sterile Filtered clear colorless solution.
Immunogen
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Ig Subclass
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Purification Method
Purified monoclonal IgG by protein A chromatography.
Formulation
1x PBS and 0.05% sodium nitrate.
Storage Procedures
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Stability / Shelf Life
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Applications
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Safety Data Sheet
SDS
Usage
Mabioway's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Shipping Conditions
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Solubility
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Titer
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