Cat. No.
MABL-5944
Type
Mouse Anti Human Monoclonal.
Clone No
NYRhc-myc.
Shipped
At Room Temperature
Description
c-myc, Mouse anti Human
Synonyms
MYC, CMYC, C-MYS, V-MYC, P64.
Introduction
c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Physical Appearance
/
Immunogen
synthetic peptides.
Ig Subclass
mouse IgG1.
Purification Method
Protein A.
Formulation
1mg/ml in PBS (after reconstitution).
Storage Procedures
Antibody is shipped lyophilized at ambient temperature.
Stability / Shelf Life
/
Applications
/
Safety Data Sheet
SDS
Usage
Mabioway's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Shipping Conditions
/
Solubility
Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Titer
By Western blot 1:2,000 dilution will yield a strong band in WB.
