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Anti-Bla g 2 mAbs

简要描述:

This antibody binds to the N-terminal lobe of Bla g 2.

产品参数:

Cat. No.:MABL-3328

Species:Engineer

Species Reactivity:German Cockroach (B. germanica)

Type:Recombinate

Application:crystallography, ELISA

详细介绍

Key features and   details


Cat. No.

MABL-3328

Name

Anti-Bla g 2  mAbs

Clone No.

AFD-7C11

From

Recombinant Antibody

Isotype

Engineer antibody

Application

crystallography, ELISA

Species Reactivity

German Cockroach (B. germanica)

Basic Information


Specificity

This antibody binds to the N-terminal lobe of Bla g 2.

Alternative Name

Cockroach Allergen; Aspartic protease Bla g 2; Blattella germanica allergen

UniProt

P54958

Immunogen

Bla g 2, a major cockroach allergen.

Application Notes

This antibody binds to Bla g 2 via an epitope commonly used by allergogenic IgE, however distinct from the epitope   used by anti-Bla g 2 antibody clone 4C3 also available through Absolute   Antibody. Both antibodies may be used in a sandwich ELISA. F(ab')2 versions   of this antibody have been used in co-crystallization studies of Bla g 2.

Antibody First   Published

Li et al. Crystal   structure of a dimerized cockroach allergen Bla g 2 complexed with a   monoclonal antibody. J Biol Chem. 2008 Aug 15;283(33):22806-14. PMID:18519566  

Note on publication

Describes isolation of   B-cells from patients, preparation of cDNA libraries as well as generation and characterization of anti-Phl p 5 scFv 4.2 .

COA Information For reference only, actual COA shall prevail

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.


 


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