Anti-Bla g 2 mAbs

Cat. No.

MABL-3333

Name

Anti-Bla g 2  mAbs

Clone No.

AFD-4C3

From

Recombinant Antibody

Isotype

Engineer antibody

Application

crystallization, ELISA

Species Reactivity

German Cockroach (B. germanica)

Basic Information

Specificity

This antibody binds to the C-terminal lobe   of Bla G 2, via an epitope containing a carbohydrate moiety (on Asn268,   however non-essential for binding, though a 40-fold reduction in affinity is   observed).

Alternative Name

Cockroach Allergen; Aspartic protease Bla g 2; Blattella germanica allergen

UniProt

P54958

Immunogen

Bla g 2, a major cockroach allergen.

Application Notes

This antibody binds to Bla g 2 via an   epitope distinct from the epitope used by anti-Bla g 2 antibody clone 7C11   also available through Absolute Antibody. Both antibodies may be used in a   sandwich ELISA.

Antibody First   Published

Li et al. Carbohydrates contribute to the   interactions between cockroach allergen Bla g 2 and a monoclonal antibody J   Immunol. 2011 Jan 1; 186(1): 333–340. PMID:21123808

Note on publication

Describes the generation   and use of this antibody in co-crystallization study.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.