Key features and details | |
Cat. No. | MABL-3363 |
Name | Anti-Der p 2 mAbs |
Clone No. | AFD-H5 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | chimera studies, SPR |
Species Reactivity | Dermatophagoides pteronyssinus Immunogen |
Basic Information | |
Specificity | H5 binds a distinct epitope to clones H10 and H3. |
Alternative Name | Mite Allergen; Mite group 2 allergen Der p 2; Allergen Der p II; DPX |
UniProt | P49278 |
Immunogen | The antibody was generated by immunising mice with Der p 2. |
Application Notes | The binding of chimeric H5 to Der p 2 was confirmed using SPR, with a Kd value of approximately 30 nM. SPR also showed it binds distinct epitopes to clones H3 and H10 (Christensen et al., 2008; PMID: 18572230). |
Antibody First Published | Christensen et al. Several distinct properties of the IgE repertoire determine effector cell degranulation in response to allergen challenge J Allergy Clin Immunol. 2008 Aug;122(2):298- 304. PMID:18572230 |
Note on publication | Descibes the original production of the antibody and its characterisation through SPR. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
