Cat. No.
MABL-3769
Application
ELISA
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
4A6
From
Recombinant Antibody
Specificity
This antibody binds CA19-9, which is a mucin-type glycoprotein tumor marker, a glycolipid on the cell membrane. It is known to play a role in cell-to-cell recognition processes. Elevated levels of CA 19-9 may indicate advanced cancer in the pancreas, but it is also associated with noncancerous conditions, including gallstones, pancreatitis, cirrhosis of the liver, and cholecystitis.
Alternative Names
CA 19-9; sialyl-Lewis; Carbohydrate antigen 19-9; tumor marker
UniProt
Immunogen
The original antibody was generated by immunizing BALB/c mice with carbohydrate antigen 19-9.
Application Notes
This antibody was used in a double antibody sandwich ELISA where antibody 4A6 is a capture antibody, and the antibody 4G2 is a detection antibody. The detection method had high sensitivity, with the LOD of CA19-9 detection as 21.333ng/mL (CN114573700).
Antibody First Published
Note on publication
Size
250 μg Purified antibody.
Concentration
151 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 450.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 170⁰C.
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