Cat. No.
MABL-3803
Application
IB, ICC, WB, ELISA, IHC
Isotype
Engineer antibody
Species Reactivity
n/a
Clone No.
FU-MK-1
From
Recombinant Antibody
Specificity
Alternative Names
GA7332 TA; Tumour-associated antigen GA733-2
UniProt
Immunogen
Cancerous ascites derived from a poorly differentiated adenocarcinoma of the stomach.
Application Notes
The antibody binds specifically to GA733-2, a tumour-associated transmembrane antigen expressed on adenocarcinomas of the colon, stomach, esophagus, breast and lung. The monoclonal antibody FU-MK-1 binds to cholangiocarcinomas, a tumour composed of mutated epithelial cells which originates in the bile ducts, but does not recognize hepatocellular carcinomas. Due to its specificity, the monoclonal antibody can be used as an antigenic marker in histopathological examination of tissues.
Antibody First Published
Watanabe R, Johzaki H, Iwasaki H, Kikuchi M, Ikeda S. A new tumor- associated antigen defined by a monoclonal antibody directed to gastric adenocarcinoma. Cancer. 1993 Apr 15;71(8):2439-47. PMID:7680948
Note on publication
Describes the generation of a monoclonal antibody that recognises the tumour- associated antigen GA733-2 , and can be used as an antigenic marker for gastric adenocarcinoma.
Size
284 μg Purified antibody.
Concentration
185 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 484.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 204⁰C.
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