Cat. No.
MABL-3844
Application
IHC-P, in vivo, IP, WB, ELISA, IF, IHC-Fr
Isotype
Engineer antibody
Species Reactivity
Monkey, Rabbit, Rat, Human, Mouse
Clone No.
PAb421
From
Recombinant Antibody
Specificity
Recognises the mammalian mutant and wild-type p53 protein and reacts with an epitope between amino acid residues 370 and 378 (near the C-terminus of the protein), corresponding to the sequence "KKGQSTSRHK".
Alternative Names
Tumor suppressor p53; Cellular tumor antigen p53
UniProt
P04637
Immunogen
Synthetic peptide corresponding to aa 371-380 of human p53.
Application Notes
Antibody First Published
Harlow E, Crawford LV, Pim DC, Williamson NM. Monoclonal antibodies specific for simian Virus 40 tumor antigens. J Virol. 1981 Sep;39(3):861-9. PMID:6169844
Note on publication
Describes the production and subsequent characterisation of anti-p53 monoclonal antibody clones.
Size
325 μg Purified antibody.
Concentration
226 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 525.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 245⁰C.
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