Cat. No.
MABL-3848
Application
ELISA, IHC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
11d1e5E10
From
Recombinant Antibody
Specificity
This antibody binds an epitope between amino acids 370 and 750 of the human PSMA. Prostate-specific membrane antigen (PSMA) is a type II integral membrane glycoprotein belonging to the M28 peptidase family. It acts as a glutamate carboxypeptidase on different alternative substrate. It is highly expressed in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer.
Alternative Names
PSM; FOLH1; FOLH; FGCP; GCPII; mGCP; NAALAD1; GIG27; Prostate specific membrane antigen; Glutamate carboxypeptidase 2; Cell growth-inhibiting gene 27 protein; Folate hydrolase 1; Folylpoly-gamma-glutamate carboxypeptidase; Glutamate carboxypeptidase II; Membrane glutamate carboxypeptidase; N-acetylated-alpha-linked acidic dipeptidase I; NAALADase I; Prostate-specific membrane antigen; Pteroylpoly-gamma-glutamate carboxypeptidase
UniProt
Q04609
Immunogen
The original antibody was generated by immunizing mice with a HIS tagged human PSMA fragment (amino acids between 307 to 750).
Application Notes
The binding characterization of this antibody was done using ELISA. This antibody is also recommended for the detection of PSMA using immunohistochemistry (CN112480260).
Antibody First Published
Note on publication
Size
329 μg Purified antibody.
Concentration
230 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 529.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 249⁰C.
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