Key features and details | |
Cat. No. | MABL-014 |
Name | Anti-Cocaine mAbs |
Clone No. | AFD-GNC92H2 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | n/a |
Basic Information | |
Specificity | Specifically binds to Benzoylmethylecgonine (Cocaine) with a Kd= 4E-7, which is 100-fold difference in Kd to the carboxylic acid metabolite Benzoylmethylecgonine |
Alternative Name | Benzoylmethylecgonine |
UniProt | |
Immunogen | Benzoylecgonine-KLH conjugate. |
Application Notes | This antibody binds to cocaine, a strong stimulant used clinically as a local analgesic and vasoconstrictor, as well as illegally as a recreational drug. |
Antibody First Published | Larsen et al. 2001 Crystal Structure of a Cocaine-binding Antibody. Journal of Molecular Biology 2001; 311:9-15 PMID:11469854 |
Note on publication | Describes the generation and humanisation of a cocaine-binding antibody and the determination of its crystal structure. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |