Key features and details | |
Cat. No. | MABL-019 |
Name | Anti-NgR1 mAbs |
Clone No. | AFD-M5 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IP, WB, ELISA, FC |
Species Reactivity | Rat, Human, Mouse |
Basic Information | |
Specificity | The antibody binds to human and rat NgR1 with a Kd of 2.9 nM for both species (bivalent binding). |
Alternative Name | Nogo-66 Receptor |
UniProt | Q86UN2 |
Immunogen | (His)6-tagged fragment of rat NgR1 (amino acids 278-473). |
Application Notes | The antibody binds specifically to residues 379-448 of NgR1, a member of the Nogo- 66 receptor family which inhibits axonal growth and sporulating in the CNS. |
Antibody First Published | Hofer et al. Chimeric Rabbit/Human Fab and IgG Specific for Members of the Nogo-66 Receptor Family Selected for Species Cross-Reactivity with an improved Phage Display Vector. |
Note on publication | Describes the generation of two monoclonal rabbit antibodies against members of the Nogo-66 receptor family. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
