Key features and details | |
Cat. No. | MABL-035 |
Name | Anti-tau mAbs |
Clone No. | AFD-Tau-5 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | EM, IF |
Species Reactivity | Rat, Sheep, Human, Mouse |
Basic Information | |
Specificity | This antibody binds to sequence 210-241 of tau protein. |
Alternative Name | MAPT;DDPAC;FTDP-17;MAPTL;MSTD;MTBT1;MTBT2;PPND;PPP1R103;microtubule-associated protein tau |
UniProt | |
Immunogen | Tau protein. |
Application Notes | This antibody binds to tau in a phosphorylation independent manner. Tau proteins are abundant in the central nervous system and stabilize micrtubules. Immuno-staining can be affected by different fixation methods (see LoPresti et al. 1995). |
Antibody First Published | LoPresti P, Szuchet S, Papasozomenos SC, Zinkowski RP, Binder LI. Functional implications for the microtubule-associated protein tau: localization in oligodendrocytes. Proc Natl Acad Sci U S A. 1995 Oct 24;92(22):10369-73. PMID:7479786 |
Note on publication | Describes the use of Tau-5 in localizing tau protein to oligodendrocytes in the nervous system |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |