Anti-Kv1.2 K+ Channel mAbs

Cat. No.

MABL-067

Name

Anti-Kv1.2 K+ Channel  mAbs

Clone No.

AFD-K14/16

From

Recombinant Antibody

Isotype

Engineer antibody

Application

IB, IP, IF, IHC

Species Reactivity

Rat, Xenopus, Zebrafish, Human, Mouse

Basic Information

Specificity

This antibody is specific for the Kv1.2 voltage-gated potassium channel. It has been shown not to cross-react with other Kv1 channels.

Alternative Name

K14/16R; Potassium voltage-gated channel subfamily A member 2; KCNA2; NGK1; Voltage-gated K(+) channel; HuKIV; HBK5;   NGK1; RAK, RBK2; RCK5; MK2

UniProt

P16389

Immunogen

This antibody was raised by immunising   BALB/c mice with recombinant protein corresponding to amino acids 428-499 of human Kv1.2

Application Notes

This antibody has been used in   immunohistochemical analysis of Kv1.2 expression in sections of mouse sciatic   nerves (Montani et al, 2018) and adult rat hippocampus (Andrews et al, 2019;   PMID:30667360). This antibody has also been used in immunoblot analysis of   membranes.

Antibody First Published

Yang et al. Trafficking-dependent   phosphorylation of Kv1.2 regulates voltage-gated potassium channel cell   surface expession PNAS December 11, 2007 104 (50) 20055-20060 PMID:18056633

Note on publication

Describes the original use of this antibody   in immunofluorescence and immunoblot analysis.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.