Key features and details | |
Cat. No. | MABL-096 |
Name | Anti-JIP-2/IB-2 mAbs |
Clone No. | AFD-N135/37.2 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB, IHC |
Species Reactivity | Rat, Mouse |
Basic Information | |
Specificity | This antibody is specific for a sequence of amino acids between the 226th and 421th amino acid of the JIP-2 gene. The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAP |
Alternative Name | N135/37.2R; N135/37; C-Jun-amino-terminal kinase-interacting protein 2; JIP-2; JNK-interacting protein 2; Islet-brain-2; IB-2; JNK MAP kinase scaffold protein 2; Mitogen-activated protein kinase 8-interacting protein 2 |
UniProt | Q9ERE9 |
Immunogen | This antibody was raised by immunising BALB/c mice with Fusion protein corresponding to Mouse IB-2 aa 226-421. |
Application Notes | This antibody is recommended for the detection and analysis of JIP-2/IB-2 by western blot and immunohistochemistry. For instance, the mouse version of this antibody was used to detect JIP- 2/IB-2 by western blot in adult rat brain membranes. And it was also used to detect JIP-2/IB-2 by immunohistochemistry in adult rat brain membranes. |
Antibody First Published | Andrews et al. A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced multiplex immunolabeling of brain eLife. 2019; 8: e43322. PMID:30667360 |
Note on publication | This article describes the generation of a library of recombinant monoclonal antibodies (R-mAbs) from a pool of mAb-producing hybridomas for neuroscience research. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |