Key features and details | |
Cat. No. | MABL-138 |
Name | Anti-Versican mAbs |
Clone No. | AFD-N351/23 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ICC, WB |
Species Reactivity | Rat, Mouse |
Basic Information | |
Specificity | This antibody is specific for Versican epitope: amino acids 362-585 (glucosaminoglycan alpha domain) of mouse Versican core protein. Versican may play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid. |
Alternative Name | N351/23R; Versican core protein; Chondroitin sulfate proteoglycan core protein 2; Chondroitin sulfate proteoglycan 2; Large fibroblast proteoglycan; PG-M |
UniProt | Q62059 |
Immunogen | This antibody was raised by immunising BALB/c mice with versican epitope: amino acids 362- 585 (glucosaminoglycan alpha domain) of mouse Versican core protein. |
Application Notes | This antibody is recommended for detection and analysis of versican by immunocytochemsitry and western blot. For instance, the mouse version of this antibody was used to detect versican by immunofluorescence in adult spinal cord from versican wild-type and knockout mice. |
Antibody First Published | Andrews et al. A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced multiplex immunolabeling of brain eLife. 2019; 8: e43322. PMID:30667360 |
Note on publication | This article describes the generation of a library of recombinant monoclonal antibodies (R-mAbs) from a pool of mAb-producing hybridomas for neuroscience research. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
