Key features and details | |
Cat. No. | MABL-264 |
Name | Anti-Morphine mAbs |
Clone No. | AFD-3K11 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Species independent |
Basic Information | |
Specificity | This antibody binds morphine and also recognizes the 3-O-carboxymethyl ester of morphine. Morphine is a strong opiate that is found naturally in opium, a dark brown resin in poppies (Papaver somniferum). It is considered the classic opioid analgesic, most commonly used in pain management, morphine provides major relief to patients afflicted with pain. It is a non-synthetic narcotic with a high potential for abuse. |
Alternative Name | Morphium; opoids; ChEBI: 17303 |
UniProt | |
Immunogen | The original antibody was generated by immunizing Balb/c mice with two morphine derivative 3-O-carboxymethyl ester, conjugated to BSA. |
Application Notes | This antibody binds morphine with a binding affinity of Kd = 61nM. The binding characterization of this antibody to the 3-O-carboxymethyl ester of morphine was done using ELISA (PMID: 32219918). |
Antibody First Published | Trofimov et al. Epitope specificity of two anti-morphine monoclonal antibodies: In vitro and in silico studies. J Mol Recognit. 2020 Sep;33(9):e2846. PMID:32219918 |
Note on publication | This paper describes the characterization of two antibodies generated against morphine. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
