Key features and details | |
Cat. No. | MABL-675 |
Name | Anti-CD11 alpha/Integrin alpha-L mAbs |
Clone No. | AFD- YTH 81.5 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | FC |
Species Reactivity | Human |
Basic Information | |
Specificity | Recognizes a 180kD glycoprotein, CD11 alpha, expressed by human leukocytes, involved in cellular adhesion and costimulatory signaling. It is the target of the drug efalizumab. |
Alternative Name | CD11A; CD11a; Integrin alpha L; Integrin alpha-L; Integrin αL; ITGAL; LFA alpha-1; YTH81; YTH-81 |
UniProt | P20701 |
Immunogen | CD11 alpha/ Integrin alpha -L glycoprotein expressed in human lymphocytes. |
Application Notes | |
Antibody First Published | Clark M, Hale G, Waldmann H. Interaction of rat monoclonal antibodies with human killer cells. Adv Exp Med Biol. 1985;186:797-803 PMID:4050599 |
Note on publication | Describes the preparation of rat anti human CD11 alpha antibody and characterisation of the specificities. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
