Key features and details | |
Cat. No. | MABL-720 |
Name | Anti-CD147 mAbs |
Clone No. | AFD- 059-053 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ADCC |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for CD147. CD147 acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors. Further, in association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors. |
Alternative Name | 5F7; TCSF; Basigin; Collagenase stimulatory factor; Collagenase stimulatory factor; Extracellular matrix metalloproteinase inducer; EMMPRIN; Hepatoma-associated antigen; HAb18G; Leukocyte activation antigen M6; OK blood group antigen; Tumor cell-derived collagenase stimulatory factor |
UniProt | P35613 |
Immunogen | The original antibody was isolated by panning a phage display library against CD147. |
Application Notes | The IgG1 format of the antibody specifically bound to the cancer cells expressing CD147 (CCF-RC1, ACHN) and expresses the ADCC activity (US9388249B2). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
