Key features and details | |
Cat. No. | MABL-756 |
Name | Anti-CD19 mAbs |
Clone No. | AFD- 26D3 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB, ELISA, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for CD19. Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. |
Alternative Name | B4 antigen; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Differentiation antigen CD19; T-cell surface antigen Leu-12; LE-CD19 |
UniProt | P15391 |
Immunogen | The original antibody was generated by immunizing mice with CD19. |
Application Notes | The antibody detected the recombinant CD19 by western blot analysis. The antibody was used to stain and analyze prostate tissue, B-cell lymphoma samples and tonsil B lymphocytes by immunohistochemistry. Further, immunohistochemistry staining from 26D3 antibody and the commercial antibody, LE-CD19, were compared. Results showed that the specificity of the 26D3 antibody in tumor tissue was equivalent to the commercial antibody, while sensitive and affinity were higher than the commercial antibody (CN103880960). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
