Anti-CD1a mAbs

Cat. No.

MABL-766

Name

Anti-CD1a mAbs

Clone No.

AFD- CBT6

From

Recombinant Antibody

Isotype

Engineer antibody

Application

IP, ELISA, FC, IHC

Species Reactivity

Human

Basic Information

Specificity

 The antibody is specific for the human CD1a   protein.

Alternative Name

 T6/Leu6; T-cell surface antigen T6/Leu-6;   T6; Leu 6; hTa1 thymocyte antigen; FCB6; R4; hTa1 thymocyte antigen

UniProt

 P06126

Immunogen

 This antibody was raised by immunizing mice   with the human CD1a protein.

Application Notes

 The antibody can be used to inhibit   Sag-induced proliferation of MHC class II thymocytes (Gregory. et al, 2000).   It can increase intracellular calcium concentration in MHC class II   thymocytes if used toghether with rabbit anti-mouse antibodies (Gregory. et   al, 2000). This antibody is shown to be useful in flow cytometry (Gregory. et   al, 2000). Immunofluorescence is a method for which this antibody can also be   used (Brocks. et al, 2017). The antibody can be utilized in   immunihistochemistry to seperate human cells from cells of other animals   (Goan. et al, 2000). The antibody is also reccomended for use in ELISA and   immunoprecipitation.

Antibody First Published

 Gregory. et al Role of the CD1a molecule in   the superantigen-induced activation of MHC class II negative human thymocytes   Hum Immunol. 2000 May;61(5):427-37.PMID:10773345

Note on publication

 It describes the use of the antibody in   inhibiting the proliferation of MHC class II thymocytes.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.