Key features and details | |
Cat. No. | MABL-785 |
Name | Anti-CD20 mAbs |
Clone No. | AFD- CAT-13.6E12 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | FC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody recognises human CD20, which is a B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. |
Alternative Name | Leu16; B-lymphocyte antigen CD20; B-lymphocyte surface antigen B1; Bp35; Leukocyte surface antigen Leu-16; Membrane-spanning 4-domains subfamily A member 1; CAT 13.6E12 |
UniProt | P11836 |
Immunogen | This antibody was raised by immunising mice against CD20. |
Application Notes | CAT 13.6E12, as an anti-CD20 antibody, can be used to detect normal and neoplastic B cells in tissue sections as well as to identify CD20 via flow cytometry. This antibody was also recommended for treating primary intraocular lymphoma (WO2010076400A1). |
Antibody First Published | Fisson et al. Use of an anti-cd20 antibody for treating primary intraocular lymphoma U.S. Patent Application 13/143,056. |
Note on publication | This patent describes CAT 13.6E12 antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
