Key features and details | |
Cat. No. | MABL-797 |
Name | Anti-CD200R mAbs |
Clone No. | AFD- OX-110 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | FC |
Species Reactivity | Mouse |
Basic Information | |
Specificity | OX-110 binds specifically to CD200R proteins. CD200R is a type I membrane protein and an inhibitory receptor for the CD200/OX-2 cell surface glycoportein. CD200R acts to limit inflammation by inhibiting expression of pro-inflammatory molecules such as TNF-alpha, interferons and iNOS in response to selected stimuli. CD200R is expressed on rodent myeloid cells and is involved in regulation of macrophage function. |
Alternative Name | OX2R; Cell surface glycoprotein CD200 receptor; cell surface glycoprotein CD 200 receptor; CD200 receptor; CD 200 receptor; CD200cell surface glucoprotein receptor; CD 200 cell surface glycoprotein receptor; cell surface glycoprotein OX2 receptor; OX110; MRC OX |
UniProt | Q9ES57 |
Immunogen | OX-110 was generated from rats using immunogenic mouse fusion protein mCD200RCD4d34. |
Application Notes | OX-110 can be used to stain in FC. |
Antibody First Published | Wright et al. Characterization of the CD200 receptor family in mice and humans and their interactions with CD200. J I mmunol 171：3034-46 2003 PMID：12960329 |
Note on publication | Describes the use of OX-110 in stdying CD200R expression on isolated leukocyte populations. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
