Key features and details | |
Cat. No. | MABL-803 |
Name | Anti-CD205 mAbs |
Clone No. | AFD- NLDC145 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IB, FC, IF, IHC |
Species Reactivity | Mouse |
Basic Information | |
Specificity | This antibody is specific for murine DEC-205, a lectin endocytic receptor expressed at high levels by many dendritic cell subsets, where it mediates antigen uptake. The epitope recognised by this antibody is trypsin-sensitive. |
Alternative Name | Ly-75; NLDC-145; DEC205; DEC-205; Lymphocyte antigen 75; Ly-75 |
UniProt | Q60767 |
Immunogen | This antibody was raised by immunising Wistar rats with mouse lymph node stroma. |
Application Notes | This antibody has been used in IHC analysis of acetone-fixed mouse lymph node sections and cytospin preparations (Krall et al, 1986), and immunofluorescence analysis of epidermal sheets ( Krall et al, 1986).It has also been used in immunoblot experiments (Inaba et al, 1995) and in FC experiments to identify DEC-205-expressing cell subsets (Inaba et al, 1995; Hawiger et al, 2001). |
Antibody First Published | Kraal et al. Langerhans' cells, veiled cells, and interdigitating cells in the mouse recognized by a monoclonal antibody J Exp Med. 1986 Apr 1; 163(4)： 981–997 PMID：3950549 |
Note on publication | Describes the original generation of this antibody, and characterisation of the dendritic cell subsets to which it binds. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
