Key features and details | |
Cat. No. | MABL-932 |
Name | Anti-CD4 mAbs |
Clone No. | AFD- W3/25 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | FC, IHC |
Species Reactivity | Rat |
Basic Information | |
Specificity | Recognises a 50kDa Cell surface glycoprotein expressed by helper T cells - found on 86% of rat thymocytes, 70% of peripheral T lymphocytes and macrophages. |
Alternative Name | T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu- 3; W3/25 antigen; CD4 |
UniProt | P05540 |
Immunogen | Membraneous glycoproteins from rat thymocytes. |
Application Notes | This antibody binds to rat CD4 and is able to suppress IL2 production in the Mixed Lymphocyte Reaction Assay. |
Antibody First Published | Williams AF, Galfrè G, Milstein C. Analysis of cell surfaces by xenogeneic myeloma-hybrid antibodies: differentiation antigens of rat lymphocytes. Cell. 1977 Nov;12(3):663-73.PMID:303545 |
Note on publication | Describes the generation of the antibody, shows it recognised rat thymocytes, and analysed by immunoblotting and fluorescence activated cell sorter. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
