Anti-CD45RA or A/B mAbs

Cat. No.

MABL-989

Name

Anti-CD45RA or A/B mAbs

Clone No.

AFD- OX-30

From

Recombinant Antibody

Isotype

Engineer antibody

Application

Blocking, FC, IHC-Fr

Species Reactivity

Rat

Basic Information

Specificity

This antibody recognizes all molecular forms   of rat L-CA, and is noncompetitive with OX-1, 28 and 29 in binding to L-CA.   While purified L-CA inhibited binding of this antibody to lymph node cells,   no such inhibition of binding was seen with reduced and alkylated L-CA.

Alternative Name

PTPRC; B220; CD45; CD45 R; GP180; L-CA; LCA;   LY5; T200; protein tyrosine phosphatase; receptor type C; Receptor-type   tyrosine-protein phosphatase C

UniProt

P04157

Immunogen

This antibody was prepared by immunizing   BALB/c mice with rat lymph node glycoproteins.

Application Notes

This antibody binds all molecular forms of   rat L-CA, and consequently can be used to label thymocytes, T cells, B cells   and most bone marrow cells (Woollett, 1985).

Antibody First Published

Woollett et al. Molecular and antigenic   heterogeneity of the rat leukocyte- common antigen from thymocytes and T and   B lymphocytes. Eur J Immunol. 1985 Feb;15(2):168-73.PMID:2578966

Note on publication

Describes the original use of this antibody   in FC and blocking analysis to assess the molecular and antigenic   heterogenity of rat L-CA.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.