Key features and details | |
Cat. No. | MABL-1071 |
Name | Anti-CD68 mAbs |
Clone No. | AFD- Y-2/131/47 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ICC, IP, WB |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody recognises human CD68 antigen. CD68 is a membrane glycoprotein highly expressed in monocytes and macrophages. It is involved in phagocytosis, lysosomal metabolism and interactions with pathogens and other cells. |
Alternative Name | Macrosialin; Gp110; DKFZp686M18236; SCARD1; scavenger receptor class D, member 1; SRD1; SR-D1; CD68 molecule; CD68 antigen; Macrophage Antigen CD68; Y-2/131 |
UniProt | P34810 |
Immunogen | This antbody was raised by immunising mice with phytohaemagglutinin-activated peripheral blood mononuclear cells. |
Application Notes | IP: Y-2/131/47 antibody was used for immunoprecipitation from the material from spleen membranes (Micklem et al., 1989). ICC: This antibody was also used in immunocytochemical staining of acute promyelocytic leukaemia cells in order to establish a characteristic phenotype of the diseased cells and develop a potential diagnostic tool of this disorder (Erber et al., 1994). |
Antibody First Published | Micklem et al. A human macrophage-associated antigen (CD68) detected by six different monoclonal antibodies. Br J Haematol. 1989 Sep;73(1):6-11. PMID:2803980 |
Note on publication | This article characterises specificity of the Y-2/131/47 antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
