Key features and details | |
Cat. No. | MABL-1130 |
Name | Anti-CD80 mAbs |
Clone No. | AFD- 2F11 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA, FC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds B7-1 (CD80). |
Alternative Name | B7.1; CD28L; CD28LG; B7-1; B7; BB1; B7/BB1;T-lymphocyte activation antigen CD80; Activation B7-1 antigen; CTLA-4 counter-receptor B7.1; CTLA4L; CTLA-4L |
UniProt | P33681 |
Immunogen | The original antibody was isolated by panning a Fab type Rz human antibody library against CD80 antigen. |
Application Notes | This antibody can be used for detection of human B7-1 expressed on Raji B cells by flow cytometry. This antibody can be used for the detection of CD86 in an ELISA. This antibody showed inhibitory effect on T cell activity when used alone or in combination with anti-CD86 antibody 3A2 in an in vitro cell base assay. The use of combination of 3A2 and 2F11 resulted in better inhibition of T cell activity (WO2017105091). |
Antibody First Published | WO2017105091 |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
