Anti-CD98 mAbs

Cat. No.

MABL-1168

Name

Anti-CD98 mAbs

Clone No.

AFD- RL388

From

Recombinant Antibody

Isotype

Engineer antibody

Application

IP, stimulatory, FC

Species Reactivity

Mouse

Basic Information

Specificity

 This antibody recognises murine CD98, a   heterodimeric cell surface glycoprotein.

Alternative Name

 4F2hc; 4F2 cell-surface antigen heavy chain;   Solute carrier family 3 member 2; RL-388; 4F2; SLC3A2;

UniProt

 P10852

Immunogen

 This antibody was raised by immunising rats   with an IL 2-producing subline of the mouse T lymphoma EL4.

Application Notes

This antibody has been used in   immunoprecipitation analysis to characterise the CD98 antigen (Luscher et al,   1985) and flow cytometric analysis of CD98 expression by γδ T cells (Cao et   al, 2016). This antibody has been shown to stimulate IL-2 secretion by a T   cell lymphoma EL4 subline (EL4-6.1) in the presence of IL-1 (MacDonald et al,   1985). This antibody did not exert stimulatory effects on the parental EL4  line nor a series of ovalbumin-specific T-T hybrids (MacDonald et al, 1985).

Antibody First Published

MacDonald et al. Cell surface glycoproteins   involved in the stimulation of interleukin 1-dependent interleukin 2   production by a subline of EL4 thymoma cells. I. Functional characterization   by monoclonal antibodies. J. Immunol. December 1, 1985, 135 (6) 3944-3950   PMID:2415592

Note on publication

Describes the original generation of this   antibody.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.