Anti-CDX2 mAbs

Cat. No.

MABL-1173

Name

Anti-CDX2 mAbs

Clone No.

AFD- 12B6

From

Recombinant Antibody

Isotype

Engineer antibody

Application

WB, ELISA, IHC

Species Reactivity

Human

Basic Information

Specificity

The antibody recognises human CDX2. The CDX2   protein is a homeobox transcription factor expressed in the nuclei of   intestinal epithelial cells, playing an essential role in the development and   function of the digestive system.

Alternative Name

Homeobox protein CDX-2; CDX-3; Caudal-type   homeobox protein 2; rabbit mono-ERP2764Y; TA347

UniProt

Q99626

Immunogen

The original antibody was generated by   immunizing a mouse with the CDX2-KLH protein.

Application Notes

The antibody was used for  immunohistochemistry on stomach adenocarcinoma, showing accurate staining   location, clear staining, no non-specific staining, and clean background.   Further, immunohistochemistry staining on stomach adenocarcinoma from 12B6   antibody and the commercial antibody, rabbit mono-ERP2764Y, were compared.   Results showed the staining intensity of 12B6 antibody was significantly   higher than those of ERP2764Y, showing 12B6 antibody is more sensitive.   Moreover, the antibody and the commercial antibody TA347 were used for   immunohistochemistry on appendix tissue. Results showed that the antibody (12B6) and the commercially available antibody (TA347) were simultaneously   detected on the normal tissue chip, and the negative and positive detection results   were consistent, indicating that the specificity of the antibody in normal   tissue was equivalent to that of the commercially available antibody.

Antibody First Published

Note on publication

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.