Key features and details | |
Cat. No. | MABL-1176 |
Name | Anti-CEA mAbs |
Clone No. | AFD-806.077 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | in vivo, IHC |
Species Reactivity | Human, Mouse |
Basic Information | |
Specificity | The antibody is selective for CEA, exhibiting no cross reactivity to granulocytes. |
Alternative Name | carcinoembryonic antigen; Accession No. 96022936 |
UniProt | Q13984 |
Immunogen | The original antibody was generated by immunizing BALB/C mice with CEA.The antibody was subsequently humanized. |
Application Notes | The antibody-CPG2 conjugate showed anti-tumour activity in an ADEPT model. The antibody was employed to screen human normal and tumour tissues using sensitive three-stage indirect immunohistology on acetone-fixed, frozen cryostat sections. Further, the reactivity of the antibody was compared against A5B7. The two antibodies showed comparable results in the following tumours |
Antibody First Published | |
Note on publication | |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |