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Anti-CEA mAbs

简要描述:

The antibody is selective for CEA, exhibiting no cross reactivity to granulocytes.

产品参数:

Cat. No.:MABL-1176

Species:Engineer

Species Reactivity:Human, Mouse

Type:Recombinate

Application:in vivo, IHC

详细介绍

Key features and details


Cat. No.

MABL-1176

Name

Anti-CEA mAbs

Clone No.

AFD-806.077

From

Recombinant Antibody

Isotype

Engineer antibody

Application

in vivo, IHC

Species Reactivity

Human, Mouse

Basic Information


Specificity

 The antibody is selective for CEA, exhibiting no cross reactivity to granulocytes.

Alternative Name

 carcinoembryonic antigen; Accession No. 96022936

UniProt

 Q13984

Immunogen

 The original antibody was generated by immunizing BALB/C mice with CEA.The antibody was subsequently humanized.

Application Notes

The antibody-CPG2 conjugate showed   anti-tumour activity in an ADEPT model. The antibody was employed to screen   human normal and tumour tissues using sensitive three-stage indirect   immunohistology on acetone-fixed, frozen cryostat sections. Further, the   reactivity of the antibody was compared against A5B7. The two antibodies   showed comparable results in the following tumours

Antibody First Published


Note on publication


COA Information For reference only, actual COA shall prevail

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.


 


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