Anti-CRIPTO protein mAbs

Cat. No.

MABL-1270

Name

Anti-CRIPTO protein mAbs

Clone No.

AFD- B3F6

From

Recombinant Antibody

Isotype

Engineer antibody

Application

Blocking, FC

Species Reactivity

Human

Basic Information

Specificity

 This antibody is specific for the CRIPTO protein.

Alternative Name

 Cryptic protein; CFC1; Cryptic family protein 1

UniProt

 P0CG37

Immunogen

The original antibody was generated by   immunizing mice with a Cripto fusion protein expressed in CHO cells. The   fusion protein comprise of amino acid residues 1 to 169 of Cripto, fused to a   human IgG1 Fc domain. The humanized version was synthetically constructed by   grafting the CDRs of the original mouse version onto variable region   framework residues substantially from a human antibody chain.

Application Notes

Flow cytometry was performed on GEO cells  using this antibody (US8021661). It was assessed whether this antibody could   inhibit BT-474 tumor growth in mice (US8021661). It was assessed whether this   antibody could inhibit the growth of CLAU-6 human lung cancer cells in mice   (US8021661).

Antibody First Published

Glaser et al. Cripto binding molecules.   US8021661

Note on publication

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.