Key features and details | |
Cat. No. | MABL-1340 |
Name | Anti-Cytokeratin 19 mAbs |
Clone No. | AFD- RCK108 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IHC |
Species Reactivity | Zebrafish, Human |
Basic Information | |
Specificity | The antibody is specific for Cytokeratin 19. Cytokeratin 19 is found in most simple epithelia and non keratinized squamous epithelia with predominant focal reactivity. |
Alternative Name | K19; CK-19; Keratin type I cytoskeletal 19; Cytokeratin-19; Keratin-19 |
UniProt | P08727 |
Immunogen | The original antibody was generated by immunizing mice with cell line T24. |
Application Notes | The antibody could be used as a broad epithelial marker for carcinoma detection, due to its reproducible and highly sensitive staining. The antibody stained practically all epithelial tumours, especially adenocarcinoma, but it is negative in hepatocellular carcinoma (Kwaspen et al., 1997; PMID: 9447381). Antibody RCK108 reacts with a 40 kDa keratin (Cytokeratin 19) in immunoblot. |
Antibody First Published | |
Note on publication | |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |