Anti-D-Dimer mAbs

Cat. No.

MABL-1353

Name

Anti-D-Dimer mAbs

Clone No.

AFD- 3B6

From

Recombinant Antibody

Isotype

Engineer antibody

Application

Latex and RBC Agglutination, ELISA

Species Reactivity

Human

Basic Information

Specificity

Recognises epitopes that reside between amino acids 86 and 302 in the gamma-chain of fragment D chains of fibrinogen   (Fragment D) and other cross-linked fibrin degradation products containing   D-Dimer, but no reactivity with Fragment D or E, fibrinogen or fibrinogen   degradation products.

Alternative Name

XDP; Fragment D-dimer; Fibrin degradation   fragment; Fibrin degradation product

UniProt

P02671

Immunogen

Human cross-linked D-Dimer.

Application Notes

Antibody First Published

Bundesen P.G and Rylatt D. B. Monoclonal   antibodies with specificity for crosslinked fibrin derivatives and assay for   said derivatives. (1988) Patent US 4758524 A

Note on publication

Murine monoclonal antibody 3B6 (also   DD-3B6/22) was disclosed in patent (US4758524 A). The antibody is specific   for D-Dimer and represents the first clot-specific antibody.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.