Anti-Factor H mAbs

Cat. No.

MABL-1543

Name

Anti-Factor H mAbs

Clone No.

AFD- OX23

From

Recombinant Antibody

Isotype

Engineer antibody

Application

IP, WB, Block, ELISA

Species Reactivity

Primate, Human, Mouse

Basic Information

Specificity

This antibody binds to factor H, a cofactor   in the inactication the complement cascade.

Alternative Name

CHF; AHUS1; AMBP1; ARMD4; ARMS1; CFHL3; FH;   FHL1; HF; HF1; HF2; HUS; OX-23

UniProt

P08603

Immunogen

Native protein purified from plasma.

Application Notes

This antibody binds to Factor H and has been   used to determine Factor H levels in a sandwich ELISA assay   (Daniels-Treffandier, 2016). Alone it has no effect on Factor H activity, but   it is able to reduce the increase in cofactor activity mediated by the antibody   clone OX24.

Antibody First   Published

Sim et al. Monoclonal antibodies against the   complement control protein factor H (beta 1 H). Biosci Rep. 1983   Dec;3(12):1119-31. PMID:6199050

Note on publication

Describes the generation and functional   characterisation of this antibody.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.