Key features and details | |
Cat. No. | MABL-1551 |
Name | Anti-Factor VIII mAbs |
Clone No. | AFD- H1 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | Biacore, ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds to human Factor VIII. |
Alternative Name | anti-hemophilic factor;Factor 8; FVIII; AHF; Coagulation factor VIII |
UniProt | P00451 |
Immunogen | 2D-PAGE gel isolated human Factor VIII from lysate of human melanoma COLO-38 cells. |
Application Notes | Factor VIII (FVIII) is an essential blood-clotting protein, also known as anti-hemophilic factor (AHF). In humans, factor VIII is encoded by the F8 gene. Defects in this gene results in hemophilia A, a recessive X-linked coagulation disorder. |
Antibody First Published | Pini et al. Design and use of a phage display library. Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel. J Biol Chem. 1998 Aug 21;273(34):21769-76. PMID:9705314 |
Note on publication | Describes generation, using phage display, of antibodies with subnanomolar affinity against markers of angiogenesis. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
